Elucidation of the physiologically distinctive subunits of troponin in 1973 significantly facilitated our idea of cardiac contraction. While troponins are expressed in the two skeletal and cardiac muscle mass, there are actually isoforms of troponin I/T expressed selectively in the guts. By exploiting cardiac-restricted epitopes within just these p
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The solution lies in The actual fact that there are a number of isoforms of each and every troponin subunit which are encoded by unique genes, some of which can be expressed selectively in cardiac muscle. While TnI and TnT have unique cardiac and skeletal isoforms, they share a standard isoform of TnC: the sluggish-twitch skeletal muscle mass isofo
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